MyHealthMyData (MHMD) is a Horizon 2020 Research and Innovation Action which aims at fundamentally changing the way sensitive data are shared. MHMD is poised to be the first open biomedical information network centred on the connection between organisations and individuals, encouraging hospitals to start making anonymised data available for open research, while prompting citizens to become the ultimate owners and controllers of their health data. MHMD is intended to become a true information marketplace, based on new mechanisms of trust and direct, value-based relationships between EU citizens, hospitals, research centres and businesses.